The cognitive phenotype of childhood Myotonic Dystrophy type 1: A multicenter pooled analysis.

Even though there is clear evidence for brain involvement in childhood DM1, the cognitive phenotype is poorly understood. Our multicenter pooled analysis of neuropsychological assessments in the Dutch childhood DM1 expertise center (Radboud UMC and MUMC/Kempenhaeghe) provides an overview of common specific cognitive impairments in this group of children. Based on the results we argue for a minimal standard neuropsychological testing procedure.